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If you don’t have skinny genes, losing weight can feel like a never-ending uphill battle. You may already know that some people are predisposed to carrying extra weight and retaining fat, all because of their genes. But, being naturally predisposed to retaining fat doesn’t mean that you can’t lose weight—even

We have determined a novel new mechanism by which NAMPT regulates signaling pathways that influence major cellular fate decisions such as survival and programmed cell death. Our data clearly indicate that NAMPT-mediated effects on EC apoptosis are not triggered by iNAMPT-dependent NMN synthesis but rather involve eNAMPT secretion and subsequent